The woman's ex-boyfriend, Richard Hemphill, 27, is wanted for questioning in the deadly shooting, police said. He has been considered a person of interest but has not been charged.
Houston police said a woman called 911 saying she had been shot in the back. She was taken to a hospital where she was later pronounced dead.
Investigators said this started out with an argument between the victim and her ex-boyfriend. The woman was home with her current boyfriend, his brother and her sister.
There were also two young children at the apartment when this all happened, police said. One of the children might be the child of the victim and her ex-boyfriend.
After the ex-boyfriend tried to force his way into the apartment, there was a brief pause in the fight. Police said that is when the victim went to a back bedroom and then was shot at.
Police said they recovered rifle rounds at the scene, but no weapon.
Neighbors described hearing the commotion and said multiple shots were fired.
"After I heard that it made me just get out of my bed and go check on my daughters," said Kendrick lane.
Police are looking for any information on Hemphill and the vehicle he was driving.
If you have any information that could help police locate him, call 713-308-3600 or Crime Stoppers at 713-222-8477.