Police responded to reports of a woman who had been shot. When they arrived, they say they discovered the body of the 32-year-old woman in the street. Her name hasn't been released.
Homicide investigators believe she was shot in the chest while backing out of a driveway in a black Mercedes-Benz.
As the woman fell out of the car, the vehicle was still in gear at the time of the shooting, and rolled down the street before crashing into a pile of trash and a mailbox.
Witnesses told officers they saw a silver sedan leaving the scene shortly after the shooting.
Detectives don't know the motive for the shooting or if it was random.
Police say they have no other information and are asking anyone who may know something to contact HPD's Homicide Division at 713-308-3600 or Crime Stoppers at 713-222-TIPS (8477).