HOUSTON — Four Houston police officers were shot Monday afternoon while serving a narcotics warrant in southeast Houston.

Two of those officers are in critical condition and were undergoing surgery Monday night at Memorial Hermann Hospital. Chief Acevedo said both of the critically injured were shot in the neck.  

Two other officers are stable and are expected to make a full recovery. One of them, who was shot in the shoulder, was released from the hospital Monday night.

A fifth officer suffered a knee injury during the shootout and underwent surgery. He remains in the hospital. 

"We are sick and tired of having targets on our back,"  HPOU President Joe Gamaldi said at the hospital. "We are sick and tired of having dirtbags trying to take our lives when all we’re trying to do is protect this community and protect our families. Enough is enough."

Houston Police Chief Art Acevedo and Mayor Sylvester Turner also rushed to Memorial Hermann. 

They joined police officers and held hands in a circle, heads bowed in prayer led by an HPD chaplain. The mayor and chief also met with some of the officers' families. 

"This has been a tough day for this city," Mayor Turner said. "Please pray for our police officers."

Two suspects, a male and a female, are dead inside the house where the officers were serving a warrant for black tar heroin when gunfire broke out.

"A neighbor had the courage to call police and tell them that the suspects were dealing dope from the house," Acevedo said. 

HPD and Harris County Sheriff's Office SWAT teams sent robots in the house to make sure there were no other suspects before allowing nearby residents back into their homes.

The shooting happened just before 4 p.m. in a residential neighborhood in the 7800 block of Harding. That's just a few blocks from Milby High School.

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The gunshots stopped Gloverdale residents in their tracks including Rosie Tellez, who was driving home at the time.

“There were gunshots so I pulled over,” Tellez said.

She then took out her phone and started recording. In one of the videos, you can see an officer running from the scene. He had been shot in the arm. A second video shows officers rendering aid on a second officer who had been shot in the leg.

WATCH: Shocked neighbors saw shootout happen

Tellez said the officer who had been shot in the arm rested on the back of her car, waiting for an ambulance.

“They were just standing there trying to catch their breath," she said.

Moments later, streets were blocked off as neighbors watched worried and prayer for the injured officers.

“My nephew is an officer so, you know, I pray deeply...I hope they’re OK and have a full recovery,” Tellez said.

“I’m hoping that any policeman that got injured, that they were OK because they are our heroes here,” said another resident named Rose. “So I’m just praying that they’ll all be saved.”

The names of the injured officers have not been released because some of them are undercover.