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HOUSTON (AP) -- Coco Crisp, Jed Lowrie and Seth Smith homered to back up a solid performance by starter Bartolo Colon in his return from a drug suspension, and the Oakland Athletics beat the Houston Astros 6-3 on Saturday night.

It was the first appearance for Colon (1-0) since he received a 50-game suspension for a positive testosterone test Aug. 22. He allowed eight hits and three runs without a walk in six innings for the win.

Crisp homered for the second straight game with a solo shot in the fourth that put Oakland up 1-0.

Lowrie, who spent last season with the Astros, added a solo homer in Oakland s four-run sixth inning. Derek Norris gave the A s the lead with a run-scoring single later in the sixth.

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