UPDATE (6:20 p.m. Tuesday): All mainlanes have reopened.
All mainlanes are shut down eastbound on I-10 at Houston Avenue as of Tuesday evening.
TxDOT officials say a large truck lost a heavy load on the freeway. A bridge may have also been struck.
It is unclear at this time when the lanes will reopen. TxDOT officials are asking drivers to be patient and seek alternative routes.
Westbound lanes of the Katy Freeway at the 610 West Loop remain closed after a hazmat spill Tuesday morning. Expect the freeway to be closed through rush hour, according to TxDOT officials.