The Texans depth will be tested against Jacksonville as several key players will not play against the Jaguars.

Starters Will Fuller V and Vince Wilfork are both inactive.

Fuller’s absence is an extra concern because the Texans were already without Jaelen Strong. Braxton Miller will start in Fuller’s place. Expect Stephen Anderson to also get additional reps as well.

D.J. Reader will start in place of Wilfork who is missing his first game of the season.

CB A.J. Bouye will also miss his first game. The Texans secondary will get tested against Blake Bortles and his talented duo at wide receiver of Allen Robinson and Allen Hurns.

Bouye sprained his ankle during Friday’s practice.

Other inactives for the Texans include QB Brandon Weeden, RB Jonathan Grimes and LB Brian Peters who hasn’t played since injuring his leg against Minnesota.